Examine

Welcome to the Examine page, this is where I keep all the studies I have individually read, critiqued, taken notes on, and for each I have created a video. This library is rich with topics from skin care, fasting, nutrition, and many other subjects. Enjoy. 

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[S45] CYP1A2 genotype and acute effects of caffeine on resistance exercise, jumping, and sprinting performance

[S45] CYP1A2 genotype and acute effects of caffeine on resistance exercise, jumping, and sprinting performance

This study investigates the role caffeine metabolism genes have on resistance training performance

[S44] Effects of Acute caffeine ingestion on resistance training performance and perceptual responses during repeated sets to failure

[S44] Effects of Acute caffeine ingestion on resistance training performance and perceptual responses during repeated sets to failure

This study investigates the effect of caffeine consumption on resistance training performance.

[S38] Diets High in Protein or Saturated Fat Do Not Affect Insulin Sensitivity or Plasma Concentrations of Lipids and Lipoproteins in Overweight and Obese Adults

[S38] Diets High in Protein or Saturated Fat Do Not Affect Insulin Sensitivity or Plasma Concentrations of Lipids and Lipoproteins in Overweight and Obese Adults

This study investigates the impact protein (and saturated fats) have on insulin sensitivity.

[S48] The effect of caffeine ingestion on 8 km run performance in a field setting

[S48] The effect of caffeine ingestion on 8 km run performance in a field setting

This study investigates the role caffeine has on endurance performance measured by running.

[S47] Caffeine has a small effect on 5-km running performance of well-trained and recreational runners

[S47] Caffeine has a small effect on 5-km running performance of well-trained and recreational runners

This study investigates the role caffeine has on endurance performance measured by running.

[S46] The effects of different doses of caffeine on endurance cycling time trial performance

[S46] The effects of different doses of caffeine on endurance cycling time trial performance

This study investigates the role caffeine has on endurance performance measured by cycling.

[S40] Reprogramming of fatty acid metabolism in cancer

[S40] Reprogramming of fatty acid metabolism in cancer

This review pulls together the literature on how fat related enzymes and fat, itself, affect cancer.

[S34] A high-carbohydrate diet lowers the rate of adipose tissue mitochondrial respiration

[S34] A high-carbohydrate diet lowers the rate of adipose tissue mitochondrial respiration

This study investigates the effects various amounts of carbohydrates have on mitochondrial respiration (energy production) in fat cells.

[31] Palmitate acutely induces insulin resistance in isolated muscle from obese but not lean humans

[31] Palmitate acutely induces insulin resistance in isolated muscle from obese but not lean humans

This study investigates how saturated fat differently affects overweight and lean individuals' insulin sensitivity.

[S35] Effects of a low carbohydrate diet on energy expenditure during weight loss maintenance: randomized trial

[S35] Effects of a low carbohydrate diet on energy expenditure during weight loss maintenance: randomized trial

This study investigates the effect of carbohydrate consumption on metabolism.

[S32] Mitochondrial Dynamics in the Regulation of Nutrient Utilization and Energy Expenditure

[S32] Mitochondrial Dynamics in the Regulation of Nutrient Utilization and Energy Expenditure

This review investigates the role nutrition (over and under nutrition) affect mitochondrial behavior.

[S30] Dietary palmitate and oleate differently modulate insulin sensitivity in human skeletal muscle

[S30] Dietary palmitate and oleate differently modulate insulin sensitivity in human skeletal muscle

This study investigates how the consumption of saturated fat or unsaturated fat affects insulin sensitivity in the muscle of people.

[S28] Different effects of oleate vs. palmitate on mitochondrial function, apoptosis, and insulin signaling in L6 skeletal muscle cells: role of oxidative stress

[S28] Different effects of oleate vs. palmitate on mitochondrial function, apoptosis, and insulin signaling in L6 skeletal muscle cells: role of oxidative stress

This study investigates the effect of saturated fat and unsaturated fat on insulin signaling, as well as mitochondrial function, in isolated muscle cells.

[27] Protection from Palmitate-Induced Mitochondrial DNA Damage Prevents from Mitochondrial Oxidative Stress, Mitochondrial Dysfunction, Apoptosis, and Impaired Insulin Signaling in Rat L6 Skeletal Muscle Cells

[27] Protection from Palmitate-Induced Mitochondrial DNA Damage Prevents from Mitochondrial Oxidative Stress, Mitochondrial Dysfunction, Apoptosis, and Impaired Insulin Signaling in Rat L6 Skeletal Muscle Cells

This study investigates the role saturated fat (palmitate) has on mitochondrial function and insulin signaling in muscle cells.

[S26] Multiple pathways are involved in palmitic acid-induced toxicity

[S26] Multiple pathways are involved in palmitic acid-induced toxicity

This study aims to show the effects of saturated fat palmitate on various markers of cell health

[S25] Metabolic regulation of mitochondrial dynamics

[S25] Metabolic regulation of mitochondrial dynamics

This review compiles all the research (up to 2016) on mitochondrial behavior and regulation in the context of metabolism.

[S20] Metabolism of a-linolenic acid in humans

[S20] Metabolism of a-linolenic acid in humans

This study investigates how alpha-linolenic acid (ALA) is metabolized when consumed.

[S23] Newly born peroxisomes are a hybrid of mitochondrial and ER-derived pre-peroxisomes

[S23] Newly born peroxisomes are a hybrid of mitochondrial and ER-derived pre-peroxisomes

This study investigates where peroxisomes originate.

[S21] Ketones Elicit Distinct Alterations in Adipose Mitochondrial Bioenergetics

[S21] Ketones Elicit Distinct Alterations in Adipose Mitochondrial Bioenergetics

This study investigates how ketones (and the ketogenic diet) affects fat tissue mitochondria.

[S22] Insulin selectively reduces mitochondrial uncoupling in brown adipose tissue in mice

[S22] Insulin selectively reduces mitochondrial uncoupling in brown adipose tissue in mice

This study investigates how insulin affects UCP and PGC1alpha proteins in fat cells -thereby impacting mitochondrial metabolism.

[S24] Mitochondrial Fission Governed by Drp1 Regulates Exogenous Fatty Acid Usage and Storage in Hela Cells

[S24] Mitochondrial Fission Governed by Drp1 Regulates Exogenous Fatty Acid Usage and Storage in Hela Cells

This study aims to find out the effect of lipo toxicity (fat toxicity) on mitochondrial behavior.

[S16] Impact of a 6-week non-energy-restricted ketogenic diet on physical fitness, body composition and biochemical parameters in healthy adults

[S16] Impact of a 6-week non-energy-restricted ketogenic diet on physical fitness, body composition and biochemical parameters in healthy adults

This study investigates various health and performance measures when healthy men and women are placed on a ketogenic diet.

[S10] A Ketogenic Diet Favorably Affects Serum Biomarkers for Cardiovascular Disease in Normal-Weight Men

[S10] A Ketogenic Diet Favorably Affects Serum Biomarkers for Cardiovascular Disease in Normal-Weight Men

This study investigates the impact a low carbohydrate diet has on men's cholesterol, blood fats (triglycerides), and blood sugar, insulin. It also looks at cholesterol particle size.

[S14] Effects of a high-protein ketogenic diet on hunger, appetite, and weight loss in obese men feeding ad libitum

[S14] Effects of a high-protein ketogenic diet on hunger, appetite, and weight loss in obese men feeding ad libitum

This study investigates how a high fat, low carbohydrate diet compares against a moderate carbohydrate diet for weight loss, hunger sensation, and health markers of young, overweight men in a controlled laboratory setting

[S11] A Switch to Polyunsaturated Fatty Acid Based Ketogenic Diet Improves Seizure Control in Patients with Drug-resistant Epilepsy on the Mixed Fat Ketogenic Diet: A Retrospective Open Label Trial

[S11] A Switch to Polyunsaturated Fatty Acid Based Ketogenic Diet Improves Seizure Control in Patients with Drug-resistant Epilepsy on the Mixed Fat Ketogenic Diet: A Retrospective Open Label Trial

This study investigates the ketogenic diet composition and its impact on seizures, as well as some health markers, in a wide range of ages including infants to adults.

[S15] Effectiveness of a Very Low Calorie Ketogenic Diet on Testicular Function in Overweight/Obese Men

[S15] Effectiveness of a Very Low Calorie Ketogenic Diet on Testicular Function in Overweight/Obese Men

This study investigates how a calorie restricted ketogenic diet impacts overweight, middle aged men in terms of their weight, cholesterol, blood sugar, insulin, testosterone, and other values.

[S9] Very Low-Carbohydrate and Low-Fat Diets Affect Fasting Lipids and
Postprandial Lipemia Differently in Overweight Men

[S9] Very Low-Carbohydrate and Low-Fat Diets Affect Fasting Lipids and
Postprandial Lipemia Differently in Overweight Men

This study shows the effect of a low carbohydrate, high fat diet on overweight, but otherwise healthy, young men and their overall health markers (cholesterol, blood sugar, etc.).

[S8] An Isoenergetic Very Low Carbohydrate Diet Improves Serum HDL
Cholesterol and Triacylglycerol Concentrations, the Total Cholesterol to
HDL Cholesterol Ratio and Postprandial Lipemic Responses Compared
with a Low Fat Diet in Normal Weight, Normolipidemic Women

[S8] An Isoenergetic Very Low Carbohydrate Diet Improves Serum HDL
Cholesterol and Triacylglycerol Concentrations, the Total Cholesterol to
HDL Cholesterol Ratio and Postprandial Lipemic Responses Compared
with a Low Fat Diet in Normal Weight, Normolipidemic Women

This study investigates how a low carb diet compares against a low fat diet for cholesterol and blood fats, along with cholesterol particle size, in young, healthy women.

[S12] The Muscle Protein Synthetic Response to Meal Ingestion Following Resistance-Type Exercise

[S12] The Muscle Protein Synthetic Response to Meal Ingestion Following Resistance-Type Exercise

This scientific review aims to concentrate all of the research on protein and its effect in muscle growth across a variety of conditions.

[S6] Effects of Time-Restricted Eating on Weight Loss and Other Metabolic Parameters in Women and Men With Overweight and Obesity: The TREAT Randomized Clinical Trial

[S6] Effects of Time-Restricted Eating on Weight Loss and Other Metabolic Parameters in Women and Men With Overweight and Obesity: The TREAT Randomized Clinical Trial

This study investigates if putting people on an intermittent fasting (time restricted diet, 16 hours) protocol, without any other nutritional intervention, has any effect in weight, body fat, lean mass, metabolism, blood sugar, and other measures in overweight people.

[S5] The human metabolic response to chronic ketosis without caloric restriction: physical and biochemical adaptation

[S5] The human metabolic response to chronic ketosis without caloric restriction: physical and biochemical adaptation

This study investigates how a ketogenic diet impacts a series of health markers like cholesterol, blood sugar, and more in young men.

[S4] A Ketogenic Low-Carbohydrate High-Fat Diet Increases LDL Cholesterol in Healthy, Young, Normal-Weight Women: A Randomized Controlled Feeding Trial

[S4] A Ketogenic Low-Carbohydrate High-Fat Diet Increases LDL Cholesterol in Healthy, Young, Normal-Weight Women: A Randomized Controlled Feeding Trial

This study aims to find out how a strict ketogenic diet affects healthy women in outcomes of cholesterol, mainly.

[S3] Differential Metabolic Effects of Saturated Versus Polyunsaturated Fats in Ketogenic Diets

[S3] Differential Metabolic Effects of Saturated Versus Polyunsaturated Fats in Ketogenic Diets

This study aims to find out how a high fat, low carbohydrate diet focused on saturated or unsaturated fat affects cholesterol, blood sugar, ketones, and more.

Lipids activate skeletal muscle mitochondrial fission and quality control networks to induce insulin resistance in humans

Lipids activate skeletal muscle mitochondrial fission and quality control networks to induce insulin resistance in humans

This study aims to find out how fat in the blood stream affects mitochondria and insulin resistance.

[S2] Effect of low carbohydrate high fat diet on LDL cholesterol and gene expression in normal-weight, young adults: A randomized controlled study

[S2] Effect of low carbohydrate high fat diet on LDL cholesterol and gene expression in normal-weight, young adults: A randomized controlled study

This study aims to find out how the ketogenic diet affects cholesterol in healthy, normal weight individuals.

[S1] Long-term effects of a ketogenic diet in obese patients

[S1] Long-term effects of a ketogenic diet in obese patients

This study aims to find out how the ketogenic diet affects cholesterol in overweight individuals

Alcohol ingestion impairs maximal post-exercise rates of myofibrillar protein synthesis following a single bout of concurrent training

Alcohol ingestion impairs maximal post-exercise rates of myofibrillar protein synthesis following a single bout of concurrent training

This study aims to look at how alcohol affects protein synthesis in exercised muscle.

Ketogenic diets inhibit mitochondrial biogenesis and induce cardiac fibrosis

Ketogenic diets inhibit mitochondrial biogenesis and induce cardiac fibrosis

This study aims to investigate the impact the ketogenic diet and certain ketones have on heart fibrosis and heart cell death.

The physiological function of the agouti-related peptide gene: the control of weight and metabolic rate

The physiological function of the agouti-related peptide gene: the control of weight and metabolic rate

This study investigates the association between being overweight and brain centric hunger hormones.

Energy Metabolic Profile of Mice after Chronic Activation of Central NPY Y1, Y2, or Y5 Receptors

Energy Metabolic Profile of Mice after Chronic Activation of Central NPY Y1, Y2, or Y5 Receptors

This study looks at the affect neuropeptide Y has on metabolism, hunger, fat gain, as well as the receptor the protein functions through.

Effects of eight weeks of time-restricted feeding (16/8) on basal metabolism, maximal strength, body composition, inflammation, and cardiovascular risk factors in resistance-trained males

Effects of eight weeks of time-restricted feeding (16/8) on basal metabolism, maximal strength, body composition, inflammation, and cardiovascular risk factors in resistance-trained males

This study investigates the impact intermittent fasting has on body fat, muscle mass, inflammation, and insulin, blood sugar.

Finasteride: A Review of its Use for Male Pattern Baldness

Finasteride: A Review of its Use for Male Pattern Baldness

This scientific review investigates the evidence for finasteride for stopping and reversing hair loss.

Impact of weight loss on cortisol secretion in obese men with and without metabolic syndrome features

Impact of weight loss on cortisol secretion in obese men with and without metabolic syndrome features

This study investigates the differences in cortisol between overweight and lean individuals, as well as the impact weight loss has on cortisol levels.

The physiological function of the agouti-related peptide gene: the control of weight and metabolic rate

The physiological function of the agouti-related peptide gene: the control of weight and metabolic rate

This scientific review explains the role of Agouti related Peptide (AgRP) on hunger, mainly.

Physiological role of somatostatin on growth hormone regulation in humans

Physiological role of somatostatin on growth hormone regulation in humans

This scientific review discusses Human Growth Hormone and how it is regulated.

Fructose and Sucrose Intake Increase Exogenous Carbohydrate Oxidation during Exercise

Fructose and Sucrose Intake Increase Exogenous Carbohydrate Oxidation during Exercise

This study investigates the effect from glucose, fructose, and sucrose (table sugar) consumption on endurance exercise metabolism and intestinal discomfort.

Leucine, glucose, and energy metabolism after 3 days of fasting in healthy human subjects

Leucine, glucose, and energy metabolism after 3 days of fasting in healthy human subjects

This study aims to find out what happens to metabolism (resting metabolism, protein breakdown, etc.), as well as hormonal changes to a strict 3 day water fast.

Insulin-dependent modulation of plasma ghrelin and leptin concentrations is less pronounced in type 2 diabetic patients

Insulin-dependent modulation of plasma ghrelin and leptin concentrations is less pronounced in type 2 diabetic patients

This study aims to investigate the effect insulin has on the hunger hormone ghrelin and the satiety/energy state sensing hormone leptin in healthy and diabetic individuals.

Oral creatine monohydrate supplementation
improves brain performance: a double-blind,
placebo-controlled, cross-over trial

Oral creatine monohydrate supplementation
improves brain performance: a double-blind,
placebo-controlled, cross-over trial

This study investigates the affect creatine supplementation has on protecting the brain after brain injury (like collision).