top of page

Examine

Welcome to the Examine page, this is where I keep all the studies I have individually read, critiqued, taken notes on, and for each I have created a video. This library is rich with topics from skin care, fasting, nutrition, and many other subjects. Enjoy. 

[S117, 118, 119] GlyNAC on Age Reversal

[S117, 118, 119] GlyNAC on Age Reversal

These studies investigate how supplementation with GlyNAC may reverse several aspects of aging.

[S75] The pathophysiology of hypertension in patients with obesity.

[S75] The pathophysiology of hypertension in patients with obesity.

This scientific review covers the literature relating obesity to hypertension.

[S74, 77, 83, 86, 88, 90] Long Term Sucralose Consumption on Insulin Resistance.

[S74, 77, 83, 86, 88, 90] Long Term Sucralose Consumption on Insulin Resistance.

These studies look at the effect of sucralose consumption over weeks and months on insulin resistance measures.

[S82, 84, 85, 87, 89] One Dose Sucralose on Insulin Sensitivity

[S82, 84, 85, 87, 89] One Dose Sucralose on Insulin Sensitivity

These studies look at the effect of one bolus of sucralose on blood glucose levels and insulin levels to find the effect on insulin sensitivity.

[S92] Recent advances and future avenues in understanding the role of adipose tissue cross talk in mediating skeletal muscle mass and function with ageing

[S92] Recent advances and future avenues in understanding the role of adipose tissue cross talk in mediating skeletal muscle mass and function with ageing

This scientific review covers the physiological interactions between fat tissue and muscle tissue, especially in sarcopenia (age related muscle loss).

[S71] The Metabolic Role and Therapeutic Potential of the Microbiome

[S71] The Metabolic Role and Therapeutic Potential of the Microbiome

This scientific review covers everything on the microbiome and your overall health, from effects to mechanisms.

[S91] Mitochondrial Impairment in Sarcopenia

[S91] Mitochondrial Impairment in Sarcopenia

This review looks at the current evidence linking mitochondrial dysfunction to sarcopenia.

[S77] Sucralose decreases insulin sensitivity in healthy subjects: a randomized controlled trial

[S77] Sucralose decreases insulin sensitivity in healthy subjects: a randomized controlled trial

This study investigates how sucralose affects insulin sensitivity in healthy adults.

[S78] Study of the efficacy of Korean Red Ginseng in the treatment of erectile dysfunction

[S78] Study of the efficacy of Korean Red Ginseng in the treatment of erectile dysfunction

This study investigates the effectiveness of Korean Red Ginseng as a potential therapeutic for erectile dysfunction.

[S83] A 12-week randomized clinical trial investigating the potential for sucralose to affect glucose homeostasis

[S83] A 12-week randomized clinical trial investigating the potential for sucralose to affect glucose homeostasis

This study investigates the effect sucralose might have on blood glucose tolerance.

[S81] Sweet Taste Receptor Expressed in Pancreatic b-Cells Activates the Calcium and Cyclic AMP Signaling Systems and Stimulates Insulin Secretion

[S81] Sweet Taste Receptor Expressed in Pancreatic b-Cells Activates the Calcium and Cyclic AMP Signaling Systems and Stimulates Insulin Secretion

This study investigates the role sweet taste receptors and the use of saccharin and acesulfame-K on insulin secretion.

[S80] Effects of aspartame-, monk fruit-, stevia- and sucrose-sweetened beverages on postprandial glucose, insulin and energy intake

[S80] Effects of aspartame-, monk fruit-, stevia- and sucrose-sweetened beverages on postprandial glucose, insulin and energy intake

This study investigates how a single exposure to 3 non-nutritive sweeteners affects blood sugar, blood insulin, and food consumption over a 24 hour period.

[S79] Aspartame Consumption for 12 Weeks Does Not Affect Glycemia, Appetite, or Body Weight of Healthy, Lean Adults in a Randomized Controlled Trial

[S79] Aspartame Consumption for 12 Weeks Does Not Affect Glycemia, Appetite, or Body Weight of Healthy, Lean Adults in a Randomized Controlled Trial

This study investigates the role aspartame has on insulin resistance in healthy, normal weight individuals.

[S76] A randomized controlled trial to isolate the effects of fasting and energy restriction on weight loss and metabolic health in lean adults

[S76] A randomized controlled trial to isolate the effects of fasting and energy restriction on weight loss and metabolic health in lean adults

This study investigates what role alternate day fasting (ADF) has on weight loss, metabolism, and health, when calorie deficit is the same.

[S74] Effects of sucralose on insulin and glucagon-like peptide-1 secretion in healthy subjects: a randomized, double-blind, placebo-controlled trial

[S74] Effects of sucralose on insulin and glucagon-like peptide-1 secretion in healthy subjects: a randomized, double-blind, placebo-controlled trial

This study investigates the role sucralose has on insulin sensitivity and glucagon-like peptide in healthy, normal weight individuals.

[S67] A Periodic Diet that Mimics Fasting Promotes Multi- System Regeneration, Enhanced Cognitive Performance, and Healthspan

[S67] A Periodic Diet that Mimics Fasting Promotes Multi- System Regeneration, Enhanced Cognitive Performance, and Healthspan


This study investigates the effects of a Fasting Mimicking Diet on many physiological and molecular health outcomes.

[S55] Five-day water-only fasting decreased metabolic-syndrome risk factors and increased anti-aging biomarkers without toxicity in a clinical trial of normal-weight individuals

[S55] Five-day water-only fasting decreased metabolic-syndrome risk factors and increased anti-aging biomarkers without toxicity in a clinical trial of normal-weight individuals

This study investigates the role a 5 day water fast has on health.

[S49] Caffeine, CYP1A2 Genotype, and Endurance Performance in Athletes

[S49] Caffeine, CYP1A2 Genotype, and Endurance Performance in Athletes

Caffeine's role in high intensity performance, including lifting, stratified based on CYP gene expression - slow vs fast metabolizers of caffeine.

[S45] CYP1A2 genotype and acute effects of caffeine on resistance exercise, jumping, and sprinting performance

[S45] CYP1A2 genotype and acute effects of caffeine on resistance exercise, jumping, and sprinting performance

This study investigates the role caffeine metabolism genes have on resistance training performance.

[S41] Differential effects of monounsaturated, polyunsaturated and saturated fat ingestion on glucose-stimulated insulin secretion, sensitivity and clearance in overweight and obese, non-diabetic humans

[S41] Differential effects of monounsaturated, polyunsaturated and saturated fat ingestion on glucose-stimulated insulin secretion, sensitivity and clearance in overweight and obese, non-diabetic humans

This study investigates how over 24 hours of exposure to an almost pure monounsaturated, polyunsaturated, or saturated fat drink (every hour) affects insulin sensitivity.

[S42] Substituting dietary saturated fat with polyunsaturated fat changes abdominal fat distribution and improves insulin sensitivity

[S42] Substituting dietary saturated fat with polyunsaturated fat changes abdominal fat distribution and improves insulin sensitivity

This study investigates how saturated and polyunsaturated fat focused diets affect insulin sensitivity and fat distribution.

[S69] Human Beta Cell Regenerative Drug Therapy for Diabetes: Past Achievements and Future Challenges

[S69] Human Beta Cell Regenerative Drug Therapy for Diabetes: Past Achievements and Future Challenges

This scientific review looks over all the available studies on regenerating the pancreas in diabetic individuals.

[S39] Distinct effects of saturated and monounsaturated fatty acids on beta-cell turnover and function

[S39] Distinct effects of saturated and monounsaturated fatty acids on beta-cell turnover and function

This study investigates how saturated and unsaturated fats affect pancreatic beta cells and insulin secretion.

[S37] A high-fat, high-saturated fat diet decreases insulin sensitivity without changing intra-abdominal fat in weight-stable overweight and obese adults

[S37] A high-fat, high-saturated fat diet decreases insulin sensitivity without changing intra-abdominal fat in weight-stable overweight and obese adults

This study investigates how a high fat, high saturated fat diet compares against a low fat, low saturated fat diet on measures of insulin sensitivity.

[S45] CYP1A2 genotype and acute effects of caffeine on resistance exercise, jumping, and sprinting performance

[S45] CYP1A2 genotype and acute effects of caffeine on resistance exercise, jumping, and sprinting performance

This study investigates the role caffeine metabolism genes have on resistance training performance

[S44] Effects of Acute caffeine ingestion on resistance training performance and perceptual responses during repeated sets to failure

[S44] Effects of Acute caffeine ingestion on resistance training performance and perceptual responses during repeated sets to failure

This study investigates the effect of caffeine consumption on resistance training performance.

[S38] Diets High in Protein or Saturated Fat Do Not Affect Insulin Sensitivity or Plasma Concentrations of Lipids and Lipoproteins in Overweight and Obese Adults

[S38] Diets High in Protein or Saturated Fat Do Not Affect Insulin Sensitivity or Plasma Concentrations of Lipids and Lipoproteins in Overweight and Obese Adults

This study investigates the impact protein (and saturated fats) have on insulin sensitivity.

[S48] The effect of caffeine ingestion on 8 km run performance in a field setting

[S48] The effect of caffeine ingestion on 8 km run performance in a field setting

This study investigates the role caffeine has on endurance performance measured by running.

[S47] Caffeine has a small effect on 5-km running performance of well-trained and recreational runners

[S47] Caffeine has a small effect on 5-km running performance of well-trained and recreational runners

This study investigates the role caffeine has on endurance performance measured by running.

[S46] The effects of different doses of caffeine on endurance cycling time trial performance

[S46] The effects of different doses of caffeine on endurance cycling time trial performance

This study investigates the role caffeine has on endurance performance measured by cycling.

[S40] Reprogramming of fatty acid metabolism in cancer

[S40] Reprogramming of fatty acid metabolism in cancer

This review pulls together the literature on how fat related enzymes and fat, itself, affect cancer.

[S34] A high-carbohydrate diet lowers the rate of adipose tissue mitochondrial respiration

[S34] A high-carbohydrate diet lowers the rate of adipose tissue mitochondrial respiration

This study investigates the effects various amounts of carbohydrates have on mitochondrial respiration (energy production) in fat cells.

[31] Palmitate acutely induces insulin resistance in isolated muscle from obese but not lean humans

[31] Palmitate acutely induces insulin resistance in isolated muscle from obese but not lean humans

This study investigates how saturated fat differently affects overweight and lean individuals' insulin sensitivity.

[S35] Effects of a low carbohydrate diet on energy expenditure during weight loss maintenance: randomized trial

[S35] Effects of a low carbohydrate diet on energy expenditure during weight loss maintenance: randomized trial

This study investigates the effect of carbohydrate consumption on metabolism.

[S32] Mitochondrial Dynamics in the Regulation of Nutrient Utilization and Energy Expenditure

[S32] Mitochondrial Dynamics in the Regulation of Nutrient Utilization and Energy Expenditure

This review investigates the role nutrition (over and under nutrition) affect mitochondrial behavior.

[S30] Dietary palmitate and oleate differently modulate insulin sensitivity in human skeletal muscle

[S30] Dietary palmitate and oleate differently modulate insulin sensitivity in human skeletal muscle

This study investigates how the consumption of saturated fat or unsaturated fat affects insulin sensitivity in the muscle of people.

[S28] Different effects of oleate vs. palmitate on mitochondrial function, apoptosis, and insulin signaling in L6 skeletal muscle cells: role of oxidative stress

[S28] Different effects of oleate vs. palmitate on mitochondrial function, apoptosis, and insulin signaling in L6 skeletal muscle cells: role of oxidative stress

This study investigates the effect of saturated fat and unsaturated fat on insulin signaling, as well as mitochondrial function, in isolated muscle cells.

[27] Protection from Palmitate-Induced Mitochondrial DNA Damage Prevents from Mitochondrial Oxidative Stress, Mitochondrial Dysfunction, Apoptosis, and Impaired Insulin Signaling in Rat L6 Skeletal Muscle Cells

[27] Protection from Palmitate-Induced Mitochondrial DNA Damage Prevents from Mitochondrial Oxidative Stress, Mitochondrial Dysfunction, Apoptosis, and Impaired Insulin Signaling in Rat L6 Skeletal Muscle Cells

This study investigates the role saturated fat (palmitate) has on mitochondrial function and insulin signaling in muscle cells.

[S26] Multiple pathways are involved in palmitic acid-induced toxicity

[S26] Multiple pathways are involved in palmitic acid-induced toxicity

This study aims to show the effects of saturated fat palmitate on various markers of cell health

[S25] Metabolic regulation of mitochondrial dynamics

[S25] Metabolic regulation of mitochondrial dynamics

This review compiles all the research (up to 2016) on mitochondrial behavior and regulation in the context of metabolism.

[S20] Metabolism of a-linolenic acid in humans

[S20] Metabolism of a-linolenic acid in humans

This study investigates how alpha-linolenic acid (ALA) is metabolized when consumed.

[S23] Newly born peroxisomes are a hybrid of mitochondrial and ER-derived pre-peroxisomes

[S23] Newly born peroxisomes are a hybrid of mitochondrial and ER-derived pre-peroxisomes

This study investigates where peroxisomes originate.

[S21] Ketones Elicit Distinct Alterations in Adipose Mitochondrial Bioenergetics

[S21] Ketones Elicit Distinct Alterations in Adipose Mitochondrial Bioenergetics

This study investigates how ketones (and the ketogenic diet) affects fat tissue mitochondria.

[S22] Insulin selectively reduces mitochondrial uncoupling in brown adipose tissue in mice

[S22] Insulin selectively reduces mitochondrial uncoupling in brown adipose tissue in mice

This study investigates how insulin affects UCP and PGC1alpha proteins in fat cells -thereby impacting mitochondrial metabolism.

[S24] Mitochondrial Fission Governed by Drp1 Regulates Exogenous Fatty Acid Usage and Storage in Hela Cells

[S24] Mitochondrial Fission Governed by Drp1 Regulates Exogenous Fatty Acid Usage and Storage in Hela Cells

This study aims to find out the effect of lipo toxicity (fat toxicity) on mitochondrial behavior.

[S16] Impact of a 6-week non-energy-restricted ketogenic diet on physical fitness, body composition and biochemical parameters in healthy adults

[S16] Impact of a 6-week non-energy-restricted ketogenic diet on physical fitness, body composition and biochemical parameters in healthy adults

This study investigates various health and performance measures when healthy men and women are placed on a ketogenic diet.

[S10] A Ketogenic Diet Favorably Affects Serum Biomarkers for Cardiovascular Disease in Normal-Weight Men

[S10] A Ketogenic Diet Favorably Affects Serum Biomarkers for Cardiovascular Disease in Normal-Weight Men

This study investigates the impact a low carbohydrate diet has on men's cholesterol, blood fats (triglycerides), and blood sugar, insulin. It also looks at cholesterol particle size.

[S14] Effects of a high-protein ketogenic diet on hunger, appetite, and weight loss in obese men feeding ad libitum

[S14] Effects of a high-protein ketogenic diet on hunger, appetite, and weight loss in obese men feeding ad libitum

This study investigates how a high fat, low carbohydrate diet compares against a moderate carbohydrate diet for weight loss, hunger sensation, and health markers of young, overweight men in a controlled laboratory setting

[S11] A Switch to Polyunsaturated Fatty Acid Based Ketogenic Diet Improves Seizure Control in Patients with Drug-resistant Epilepsy on the Mixed Fat Ketogenic Diet: A Retrospective Open Label Trial

[S11] A Switch to Polyunsaturated Fatty Acid Based Ketogenic Diet Improves Seizure Control in Patients with Drug-resistant Epilepsy on the Mixed Fat Ketogenic Diet: A Retrospective Open Label Trial

This study investigates the ketogenic diet composition and its impact on seizures, as well as some health markers, in a wide range of ages including infants to adults.

[S15] Effectiveness of a Very Low Calorie Ketogenic Diet on Testicular Function in Overweight/Obese Men

[S15] Effectiveness of a Very Low Calorie Ketogenic Diet on Testicular Function in Overweight/Obese Men

This study investigates how a calorie restricted ketogenic diet impacts overweight, middle aged men in terms of their weight, cholesterol, blood sugar, insulin, testosterone, and other values.

bottom of page